Thursday, November 08, 2007

It's that time again!

Today is the first day of the annual meeting of the American College of Rheumatology (ACR). Each year thousands of rheumatologists, researchers, nurses, therapists and others involved in caring for people who have any of the 100 or so arthritis-related conditions descend on a major city's convention center. This year, they're all in Boston. Unfortunately, this year, I'm not. I love being at the ACR conference amidst the collaborations, explanations of what's been learned and press conferences about key scientific or clinical studies. But this year, I'm a nursing mom needed more here at home. In my place, Arthritis Today's nutrition and fitness editor, Kenna Simmons, is on site in Boston gathering up loads of information for us to share with our readers.

Today, one of her e-mails sounded ominous, as she told me about Dr. Gurkipal Singh saying there was an "impending health disaster." Dr. Singh was describing a growing problem that he calls the "gastroprotection gap." With the number of people developing arthritis on the rise due to the aging of the baby boom generation, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) has increased among older Americans. Older NSAIDs, such as aspirin, diclofenac, ibuprofen and naproxen, are known for causing gastrointestinal problems, such as ulcers. Beyond the pain of ulcers is the seriousness of the situation if they start to bleed – especially among the elderly. Bleeding ulcers can be fatal, so preventing them (and monitoring for them) is important. (Learn more about NSAIDs and side effects at www.arthritistoday.com. Click on Drug Guide.)

Protection against bleeding ulcers comes in the form of other medications, called proton pump inhibitors. These medications, such as Nexium, Prevacid and Prilosec, reduce the amount of acid in the stomach, whereas the traditional NSAIDs increase it. Dr. Singh's study shows that doctors had been getting really good at prescribing an acid reducer when they prescribed an NSAID – until the COX-2s came on the market. The COX-2s are a type of NSAID specifically designed to eliminate the gastrointestinal side effects. When the COX-2s Vioxx and Bextra were popular treatments, the rate of serious gastrointestinal complications was cut in half. But now that two of the three COX-2 drugs are no longer on the market (Celebrex still is available), and use of the COX-2s has declined, Dr. Singh found that the complication rate is jumping up again.

His study of Medicaid recipients in California shows that the percentage of people who receive medications to protect their stomachs while taking NSAIDs decreased from 35 percent to 14 percent in just one year (from 2004 to 2005). Ten years ago – before COX-2s were available and doctors had gastrointestinal complications top of mind – 79 percent of people were given stomach-protecting drugs. Since Vioxx and Bextra came off the market, gastrointestinal complications have gone up 21 percent. With the aging of the population, the increase in arthritis symptoms such as pain and swelling, and the return to using traditional NSAIDs again, Dr. Singh's study is a strong reminder for doctors to protect the stomachs of their patients when they hand out a prescription for an NSAID. And it's a call to action for patients to start questioning their doctors about the side effects of their arthritis treatments and how they can protect themselves. If both doctors and patients can take on that responsibility – and carry out their duties – I have hope that we'll avoid an impending health disaster.

Check back tomorrow to see what Kenna digs up in Beantown.

2 Comments:

At 12:25 PM, Anonymous Anonymous said...

Yes I take Naproxen,500 mg 3 times a day.It helps my muscle/skeletal pain,mainly for the morning,lasdt fall my stomach began to hurt,and my then Dr, gave me tagament.It helped a little but this fall I asked for a poetein pump inhibiter.Medicaid would not pay for any so my new Dr. gave me samples of Nexium and helped a lot. Now he did a PA and they gave me Protonix and it seems to work well.I hope that this may be passed along to those who need the info.Be sure that your Dr. is on the ball when making a Prior Auothorization.It does make a differnce if yor Dr.and staff are on the ball about PA's. Thank you.

 
At 10:10 AM, Anonymous Anonymous said...

Thanks for the great info here. Im curious... do you know of any sites/including yours that might think about having a list of all of the personal RA blogs out there? Ive read so many good ones and have my own, as well. It is deeply personal about living with RA but it seems to be helpful to others. I enjoy telling my story about what happens behind closed doors at home when one of the mates has a chronic disease like RA.
Thanks so much for your hard work and BTW - I'm the 4th kid and only girl. I'm the closest to my mom & so grateful to be here! We have a very special bond.

 

Post a Comment

<< Home